S27T (p.Ser27Thr) variant of OPRM1 (Mu-type opioid receptor)
S27T (p.Ser27Thr) in OPRM1 (Mu-type opioid receptor) is a protein-truncating change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.24 / 1. The record also includes population frequency data, published literature, and structural context.
S27T (p.Ser27Thr) variant details
- p.Ser27Thr
- gnomAD 6-154039623-AG-A
- Frameshift
- Variant Prioritization Score for Impact Estimate 0.243
- CADD 22.90
- Most common in the South Asian population (allele frequency 1.2e-05)
- Structural context available
- Literature evidence available