S27I (p.Ser27Ile) variant of OPRM1 (Mu-type opioid receptor)
S27I (p.Ser27Ile) in OPRM1 (Mu-type opioid receptor) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.29 / 1. The record also includes population frequency data and structural context.
S27I (p.Ser27Ile) variant details
- p.Ser27Ile
- ExAC rs780726314
- gnomAD rs780726314
- Missense
- Variant Prioritization Score for Impact Estimate 0.286
- REVEL 0.24
- CADD 17.80
- PolyPhen-2 0.01
- SIFT 0.09
- Most common in the Finnish in Finland (FIN) population (allele frequency 9.4e-05)
- Structural context available