S23F (p.Ser23Phe) variant of OPRM1 (Mu-type opioid receptor)
S23F (p.Ser23Phe) in OPRM1 (Mu-type opioid receptor) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.27 / 1. The record also includes population frequency data and structural context.
S23F (p.Ser23Phe) variant details
- p.Ser23Phe
- ExAC rs201728064
- Missense
- Variant Prioritization Score for Impact Estimate 0.271
- REVEL 0.20
- CADD 21.20
- PolyPhen-2 0.00
- SIFT 0.66
- Most common in the Non-Finnish European population (allele frequency 2e-05)
- Structural context available