S21R (p.Ser21Arg) variant of OPRM1 (Mu-type opioid receptor)
S21R (p.Ser21Arg) in OPRM1 (Mu-type opioid receptor) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.23 / 1. The record also includes population frequency data and structural context.
S21R (p.Ser21Arg) variant details
- p.Ser21Arg
- ExAC rs757930794
- TOPMed rs757930794
- gnomAD rs757930794
- Missense
- Variant Prioritization Score for Impact Estimate 0.225
- REVEL 0.23
- CADD 18.60
- PolyPhen-2 0.19
- SIFT 0.45
- Most common in the Non-Finnish European population (allele frequency 9e-07)
- Structural context available