S21G (p.Ser21Gly) variant of OPRM1 (Mu-type opioid receptor)
S21G (p.Ser21Gly) in OPRM1 (Mu-type opioid receptor) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.11 / 1. The record also includes population frequency data and structural context.
S21G (p.Ser21Gly) variant details
- p.Ser21Gly
- ExAC rs757930794
- TOPMed rs757930794
- gnomAD rs757930794
- Missense
- Variant Prioritization Score for Impact Estimate 0.113
- REVEL 0.03
- CADD 20.80
- PolyPhen-2 0.14
- SIFT 0.31
- Most common in the South Asian population (allele frequency 7e-05)
- Structural context available