S20L (p.Ser20Leu) variant of OPRM1 (Mu-type opioid receptor)
S20L (p.Ser20Leu) in OPRM1 (Mu-type opioid receptor) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.28 / 1. The record also includes population frequency data, published literature, and structural context.
S20L (p.Ser20Leu) variant details
- p.Ser20Leu
- gnomAD 6-154039603-C-T
- Missense
- Variant Prioritization Score for Impact Estimate 0.279
- REVEL 0.22
- MetaLR 0.01
- MetaSVM -0.94
- CADD 20.70
- PolyPhen-2 0.01
- SIFT 0.06
- Population evidence available
- Structural context available
- Literature evidence available