S11R (p.Ser11Arg) variant of OPRM1 (Mu-type opioid receptor)
S11R (p.Ser11Arg) in OPRM1 (Mu-type opioid receptor) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.17 / 1. The record also includes population frequency data, published literature, and structural context.
S11R (p.Ser11Arg) variant details
- p.Ser11Arg
- gnomAD 6-154039575-A-C
- Missense
- Variant Prioritization Score for Impact Estimate 0.169
- REVEL 0.19
- MetaLR 0.02
- MetaSVM -1.05
- CADD 8.92
- PolyPhen-2 0.14
- SIFT 0.03
- Most common in the REMAINING population (allele frequency 1.7e-05)
- Structural context available
- Literature evidence available