S11K (p.Ser11Lys) variant of OPRM1 (Mu-type opioid receptor)
S11K (p.Ser11Lys) in OPRM1 (Mu-type opioid receptor) is a protein-truncating change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.26 / 1. The record also includes population frequency data, published literature, and structural context.
S11K (p.Ser11Lys) variant details
- p.Ser11Lys
- rs1175639223
- gnomAD 6-154039575-AGC-A
- Frameshift
- Variant Prioritization Score for Impact Estimate 0.256
- CADD 24.70
- Most common in the Non-Finnish European population (allele frequency 1.5e-05)
- Structural context available
- Literature evidence available