P28T (p.Pro28Thr) variant of OPRM1 (Mu-type opioid receptor)
P28T (p.Pro28Thr) in OPRM1 (Mu-type opioid receptor) is a protein-truncating change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.40 / 1. The record also includes population frequency data, published literature, and structural context.
P28T (p.Pro28Thr) variant details
- p.Pro28Thr
- rs1031653190
- gnomAD 6-154039612-C-CCC
- Frameshift
- Variant Prioritization Score for Impact Estimate 0.395
- CADD 23.60
- Most common in the African/African-American population (allele frequency 0.00012)
- Structural context available
- Literature evidence available