P28L (p.Pro28Leu) variant of OPRM1 (Mu-type opioid receptor)
P28L (p.Pro28Leu) in OPRM1 (Mu-type opioid receptor) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.57 / 1. The record also includes population frequency data, published literature, and structural context.
P28L (p.Pro28Leu) variant details
- p.Pro28Leu
- rs929536552
- gnomAD 6-154039243-C-T
- Missense
- Variant Prioritization Score for Impact Estimate 0.573
- CADD 16.80
- SIFT 0.00
- Most common in the African/African-American population (allele frequency 2.4e-05)
- Structural context available
- Literature evidence available