N12D (p.Asn12Asp) variant of OPRM1 (Mu-type opioid receptor)
N12D (p.Asn12Asp) in OPRM1 (Mu-type opioid receptor) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.24 / 1. The record also includes population frequency data, published literature, and structural context.
N12D (p.Asn12Asp) variant details
- p.Asn12Asp
- gnomAD 6-154039578-A-G
- Missense
- Variant Prioritization Score for Impact Estimate 0.241
- REVEL 0.07
- MetaLR 0.01
- MetaSVM -0.97
- CADD 14.80
- PolyPhen-2 0.00
- SIFT 0.47
- Most common in the Non-Finnish European population (allele frequency 9e-07)
- Structural context available
- Literature evidence available