M1T (p.Met1Thr) variant of OPRM1 (Mu-type opioid receptor)
M1T (p.Met1Thr) in OPRM1 (Mu-type opioid receptor) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.04 / 1. The record also includes population frequency data, published literature, and structural context.
M1T (p.Met1Thr) variant details
- p.Met1Thr
- rs754157819
- gnomAD 6-154010517-T-C
- Missense
- Variant Prioritization Score for Impact Estimate 0.0431
- CADD 0.38
- SIFT 0.04
- Most common in the South Asian population (allele frequency 0.00021)
- Structural context available
- Literature evidence available