L34S (p.Leu34Ser) variant of OPRM1 (Mu-type opioid receptor)
L34S (p.Leu34Ser) in OPRM1 (Mu-type opioid receptor) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.25 / 1. The record also includes population frequency data, published literature, and structural context.
L34S (p.Leu34Ser) variant details
- p.Leu34Ser
- gnomAD 6-154039645-T-C
- Missense
- Variant Prioritization Score for Impact Estimate 0.245
- REVEL 0.17
- MetaLR 0.01
- MetaSVM -0.98
- CADD 22.50
- PolyPhen-2 0.00
- SIFT 0.44
- Population evidence available
- Structural context available
- Literature evidence available