L17W (p.Leu17Trp) variant of OPRM1 (Mu-type opioid receptor)
L17W (p.Leu17Trp) in OPRM1 (Mu-type opioid receptor) is a protein-truncating change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.40 / 1. The record also includes population frequency data, published literature, and structural context.
L17W (p.Leu17Trp) variant details
- p.Leu17Trp
- gnomAD 6-154039200-TC-T
- Frameshift
- Variant Prioritization Score for Impact Estimate 0.404
- CADD 22.00
- Most common in the South Asian population (allele frequency 1.3e-05)
- Structural context available
- Literature evidence available