L17S (p.Leu17Ser) variant of OPRM1 (Mu-type opioid receptor)
L17S (p.Leu17Ser) in OPRM1 (Mu-type opioid receptor) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.14 / 1. The record also includes population frequency data, published literature, and structural context.
L17S (p.Leu17Ser) variant details
- p.Leu17Ser
- gnomAD 6-154039168-T-C
- Missense
- Variant Prioritization Score for Impact Estimate 0.138
- CADD 10.10
- SIFT 0.36
- Most common in the Non-Finnish European population (allele frequency 9.3e-07)
- Structural context available
- Literature evidence available