G29C (p.Gly29Cys) variant of OPRM1 (Mu-type opioid receptor)
G29C (p.Gly29Cys) in OPRM1 (Mu-type opioid receptor) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.23 / 1. The record also includes population frequency data and structural context.
G29C (p.Gly29Cys) variant details
- p.Gly29Cys
- cosmic curated COSV57677
- gnomAD rs775097209
- Missense
- Variant Prioritization Score for Impact Estimate 0.234
- REVEL 0.20
- CADD 19.00
- PolyPhen-2 0.34
- SIFT 0.02
- Most common in the South Asian population (allele frequency 1.2e-05)
- Structural context available