D15H (p.Asp15His) variant of OPRM1 (Mu-type opioid receptor)
D15H (p.Asp15His) in OPRM1 (Mu-type opioid receptor) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.42 / 1. The record also includes population frequency data and structural context.
D15H (p.Asp15His) variant details
- p.Asp15His
- ExAC rs774232469
- TOPMed rs774232469
- gnomAD rs774232469
- Missense
- Variant Prioritization Score for Impact Estimate 0.421
- REVEL 0.26
- CADD 22.80
- PolyPhen-2 0.35
- SIFT 0.00
- Most common in the African/African-American population (allele frequency 2.4e-05)
- Structural context available