C13W (p.Cys13Trp) variant of OPRM1 (Mu-type opioid receptor)
C13W (p.Cys13Trp) in OPRM1 (Mu-type opioid receptor) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.33 / 1. The record also includes population frequency data and structural context.
C13W (p.Cys13Trp) variant details
- p.Cys13Trp
- TOPMed rs200776506
- Missense
- Variant Prioritization Score for Impact Estimate 0.33
- REVEL 0.27
- CADD 23.90
- PolyPhen-2 0.77
- SIFT 0.00
- Most common in the Non-Finnish European population (allele frequency 9e-07)
- Structural context available