C13R (p.Cys13Arg) variant of OPRM1 (Mu-type opioid receptor)
C13R (p.Cys13Arg) in OPRM1 (Mu-type opioid receptor) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.36 / 1. The record also includes population frequency data, published literature, and structural context.
C13R (p.Cys13Arg) variant details
- p.Cys13Arg
- gnomAD 6-154039581-T-C
- Missense
- Variant Prioritization Score for Impact Estimate 0.357
- REVEL 0.24
- MetaLR 0.03
- MetaSVM -1.10
- CADD 22.90
- PolyPhen-2 0.14
- SIFT 0.03
- Most common in the Non-Finnish European population (allele frequency 9e-07)
- Structural context available
- Literature evidence available