A6G (p.Ala6Gly) variant of OPRM1 (Mu-type opioid receptor)
A6G (p.Ala6Gly) in OPRM1 (Mu-type opioid receptor) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.05 / 1. The record also includes population frequency data and structural context.
A6G (p.Ala6Gly) variant details
- p.Ala6Gly
- 1000Genomes rs1799972
- ESP rs1799972
- ExAC rs1799972
- TOPMed rs1799972
- Missense
- Variant Prioritization Score for Impact Estimate 0.0476
- REVEL 0.04
- CADD 0.03
- PolyPhen-2 0.00
- SIFT 0.38
- Most common in the African/African-American population (allele frequency 0.00017)
- Structural context available