A5L (p.Ala5Leu) variant of OPRM1 (Mu-type opioid receptor)
A5L (p.Ala5Leu) in OPRM1 (Mu-type opioid receptor) is a protein-truncating change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.23 / 1. The record also includes population frequency data, published literature, and structural context.
A5L (p.Ala5Leu) variant details
- p.Ala5Leu
- gnomAD 6-154039556-CG-C
- Frameshift
- Variant Prioritization Score for Impact Estimate 0.231
- CADD 7.46
- Most common in the REMAINING population (allele frequency 1.7e-05)
- Structural context available
- Literature evidence available