A25T (p.Ala25Thr) variant of OPRM1 (Mu-type opioid receptor)
A25T (p.Ala25Thr) in OPRM1 (Mu-type opioid receptor) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.33 / 1. The record also includes population frequency data and structural context.
A25T (p.Ala25Thr) variant details
- p.Ala25Thr
- ExAC rs756777151
- gnomAD rs756777151
- Missense
- Variant Prioritization Score for Impact Estimate 0.326
- REVEL 0.26
- CADD 21.60
- PolyPhen-2 0.00
- SIFT 0.30
- Most common in the African/African-American population (allele frequency 3e-05)
- Structural context available