A25G (p.Ala25Gly) variant of OPRM1 (Mu-type opioid receptor)
A25G (p.Ala25Gly) in OPRM1 (Mu-type opioid receptor) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.48 / 1. The record also includes population frequency data, published literature, and structural context.
A25G (p.Ala25Gly) variant details
- p.Ala25Gly
- rs1049355494
- gnomAD 6-154039255-C-G
- Missense
- Variant Prioritization Score for Impact Estimate 0.479
- CADD 7.58
- SIFT 0.00
- Most common in the South Asian population (allele frequency 0.00021)
- Structural context available
- Literature evidence available