A16P (p.Ala16Pro) variant of OPRM1 (Mu-type opioid receptor)
A16P (p.Ala16Pro) in OPRM1 (Mu-type opioid receptor) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.11 / 1. The record also includes population frequency data, published literature, and structural context.
A16P (p.Ala16Pro) variant details
- p.Ala16Pro
- gnomAD 6-154039590-G-C
- Missense
- Variant Prioritization Score for Impact Estimate 0.108
- REVEL 0.04
- MetaLR 0.01
- MetaSVM -0.98
- CADD 4.92
- PolyPhen-2 0.00
- SIFT 1.00
- Most common in the Non-Finnish European population (allele frequency 9e-07)
- Structural context available
- Literature evidence available