T35A (p.Thr35Ala) variant of NRAS (GTPase NRas)
T35A (p.Thr35Ala) in NRAS (GTPase NRas) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.83 / 1. The record also includes population frequency data, published literature, and structural context.
T35A (p.Thr35Ala) variant details
- p.Thr35Ala
- gnomAD 1-114716058-T-C
- Missense
- Variant Prioritization Score for Impact Estimate 0.828
- REVEL 0.94
- CADD 30.00
- PolyPhen-2 0.93
- SIFT 0.01
- Population evidence available
- Structural context available
- Literature evidence available