T2N (p.Thr2Asn) variant of NRAS (GTPase NRas)
T2N (p.Thr2Asn) in NRAS (GTPase NRas) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.47 / 1. The record also includes population frequency data, published literature, and structural context.
T2N (p.Thr2Asn) variant details
- p.Thr2Asn
- gnomAD 1-114716156-G-T
- Missense
- Variant Prioritization Score for Impact Estimate 0.474
- REVEL 0.26
- CADD 24.60
- PolyPhen-2 0.61
- SIFT 0.02
- Most common in the Non-Finnish European population (allele frequency 9e-07)
- Structural context available
- Literature evidence available