S39Y (p.Ser39Tyr) variant of NRAS (GTPase NRas)
S39Y (p.Ser39Tyr) in NRAS (GTPase NRas) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.78 / 1. The record also includes population frequency data and structural context.
S39Y (p.Ser39Tyr) variant details
- p.Ser39Tyr
- Ensembl rs139287106
- Missense
- Variant Prioritization Score for Impact Estimate 0.779
- REVEL 0.80
- CADD 27.70
- PolyPhen-2 1.00
- SIFT 0.00
- Most common in the Non-Finnish European population (allele frequency 4e-06)
- Structural context available