S39F (p.Ser39Phe) variant of NRAS (GTPase NRas)
S39F (p.Ser39Phe) in NRAS (GTPase NRas) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.74 / 1. The record also includes population frequency data and structural context.
S39F (p.Ser39Phe) variant details
- p.Ser39Phe
- Ensembl rs139287106
- Missense
- Variant Prioritization Score for Impact Estimate 0.739
- REVEL 0.73
- CADD 28.90
- PolyPhen-2 1.00
- SIFT 0.07
- Most common in the South Asian population (allele frequency 1.3e-05)
- Structural context available