L23L (p.Leu23Leu) variant of NRAS (GTPase NRas)
L23L (p.Leu23Leu) in NRAS (GTPase NRas) is a synonymous change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.18 / 1. The record also includes population frequency data, published literature, and structural context.
L23L (p.Leu23Leu) variant details
- p.Leu23Leu
- rs771113899
- gnomAD 1-114716092-T-C
- Synonymous
- Variant Prioritization Score for Impact Estimate 0.183
- CADD 14.50
- Most common in the African/African-American population (allele frequency 3e-05)
- Structural context available
- Literature evidence available