L19V (p.Leu19Val) variant of NRAS (GTPase NRas)
L19V (p.Leu19Val) in NRAS (GTPase NRas) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.59 / 1. The record also includes population frequency data and structural context.
L19V (p.Leu19Val) variant details
- p.Leu19Val
- gnomAD rs1659158278
- Missense
- Variant Prioritization Score for Impact Estimate 0.593
- REVEL 0.65
- CADD 24.00
- SIFT 0.00
- Most common in the African/African-American population (allele frequency 2.4e-05)
- Structural context available