I21V (p.Ile21Val) variant of NRAS (GTPase NRas)
I21V (p.Ile21Val) in NRAS (GTPase NRas) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.44 / 1. The record also includes population frequency data and structural context.
I21V (p.Ile21Val) variant details
- p.Ile21Val
- Ensembl rs2101744144
- Missense
- Variant Prioritization Score for Impact Estimate 0.445
- REVEL 0.32
- CADD 24.30
- PolyPhen-2 0.55
- SIFT 0.01
- Most common in the Non-Finnish European population (allele frequency 9e-07)
- Structural context available