G12G (p.Gly12Gly) variant of NRAS (GTPase NRas)
G12G (p.Gly12Gly) in NRAS (GTPase NRas) is a synonymous change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.33 / 1. The record also includes population frequency data, published literature, and structural context.
G12G (p.Gly12Gly) variant details
- p.Gly12Gly
- rs759764705
- gnomAD 1-114716125-A-C
- Synonymous
- Variant Prioritization Score for Impact Estimate 0.331
- CADD 16.30
- Most common in the Ashkenazi Jewish population (allele frequency 0.0017)
- Structural context available
- Literature evidence available