G12F (p.Gly12Phe) variant of NRAS (GTPase NRas)
G12F (p.Gly12Phe) in NRAS (GTPase NRas) is a missense change. Clinical records from ClinVar, EBI, and UniProt describe it as likely pathogenic in the context of NRAS-related disorder. The record also includes structural context.
G12F (p.Gly12Phe) variant details
- p.Gly12Phe
- rs2101744255
- ClinGen CA2580617805
- ClinVar RCV003896707
- Likely pathogenic
- NRAS-related disorder
- Missense
- ClinVar: Likely pathogenic (NRAS-related disorder)
- EBI: Likely pathogenic (in KNEN and JMML)
- UniProt: Likely pathogenic (in KNEN and JMML)
- Structural context available