D33E (p.Asp33Glu) variant of NRAS (GTPase NRas)
D33E (p.Asp33Glu) in NRAS (GTPase NRas) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.52 / 1. The record also includes population frequency data and structural context.
D33E (p.Asp33Glu) variant details
- p.Asp33Glu
- Ensembl rs2101744031
- Missense
- Variant Prioritization Score for Impact Estimate 0.519
- REVEL 0.61
- CADD 24.60
- PolyPhen-2 0.97
- SIFT 0.06
- Most common in the Non-Finnish European population (allele frequency 9e-07)
- Structural context available