A18P (p.Ala18Pro) variant of NRAS (GTPase NRas)
A18P (p.Ala18Pro) in NRAS (GTPase NRas) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.82 / 1. The record also includes population frequency data and structural context.
A18P (p.Ala18Pro) variant details
- p.Ala18Pro
- 1000Genomes rs121913248
- Missense
- Variant Prioritization Score for Impact Estimate 0.817
- REVEL 0.83
- CADD 29.30
- SIFT 0.00
- Most common in the 1KG:CHS population (allele frequency 0.0049)
- Structural context available