G77S (p.Gly77Ser) variant of NPHS2 (Podocin)
G77S (p.Gly77Ser) in NPHS2 (Podocin) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.47 / 1. The record also includes population frequency data and structural context.
G77S (p.Gly77Ser) variant details
- p.Gly77Ser
- TOPMed rs1186309031
- gnomAD rs1186309031
- Missense
- Variant Prioritization Score for Impact Estimate 0.473
- REVEL 0.37
- CADD 21.50
- PolyPhen-2 0.01
- SIFT 0.51
- Most common in the Non-Finnish European population (allele frequency 2.7e-06)
- Structural context available