G74D (p.Gly74Asp) variant of NPHS2 (Podocin)
G74D (p.Gly74Asp) in NPHS2 (Podocin) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.34 / 1. The record also includes population frequency data and structural context.
G74D (p.Gly74Asp) variant details
- p.Gly74Asp
- ESP rs148976646
- ExAC rs148976646
- TOPMed rs148976646
- Missense
- Variant Prioritization Score for Impact Estimate 0.343
- REVEL 0.38
- CADD 16.90
- PolyPhen-2 0.03
- SIFT 0.34
- Most common in the Non-Finnish European population (allele frequency 1.5e-05)
- Structural context available