V10F (p.Val10Phe) variant of NF1 (Neurofibromin)
V10F (p.Val10Phe) in NF1 (Neurofibromin) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.34 / 1. The record also includes population frequency data, published literature, and structural context.
V10F (p.Val10Phe) variant details
- p.Val10Phe
- gnomAD 17-31095337-G-T
- Missense
- Variant Prioritization Score for Impact Estimate 0.342
- REVEL 0.18
- MetaLR 0.08
- MetaSVM -1.12
- CADD 25.40
- PolyPhen-2 0.90
- SIFT 0.01
- Population evidence available
- Structural context available
- Literature evidence available