E8* (p.Glu8Ter) variant of NF1 (Neurofibromin)

E8* (p.Glu8Ter) in NF1 (Neurofibromin) is a protein-truncating change. Clinical records from UniProt describe it as variant assessed as somatic; high impact. The available variant effect predictions contribute to a CATVariant prioritization score of 0.81 / 1. The record also includes population frequency data and structural context.

E8* (p.Glu8Ter) variant details