G28E (p.Gly28Glu) variant of MYPN (Myopalladin)
G28E (p.Gly28Glu) in MYPN (Myopalladin) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.41 / 1. The record also includes population frequency data, published literature, and structural context.
G28E (p.Gly28Glu) variant details
- p.Gly28Glu
- gnomAD 10-68121521-G-A
- Missense
- Variant Prioritization Score for Impact Estimate 0.407
- REVEL 0.22
- CADD 24.10
- PolyPhen-2 0.84
- SIFT 0.56
- Most common in the South Asian population (allele frequency 1.2e-05)
- Structural context available
- Literature evidence available