D4Y (p.Asp4Tyr) variant of MYPN (Myopalladin)
D4Y (p.Asp4Tyr) in MYPN (Myopalladin) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.40 / 1. The record also includes population frequency data, published literature, and structural context.
D4Y (p.Asp4Tyr) variant details
- p.Asp4Tyr
- gnomAD 10-68121448-G-T
- Missense
- Variant Prioritization Score for Impact Estimate 0.403
- REVEL 0.12
- CADD 26.30
- PolyPhen-2 0.83
- SIFT 0.00
- Most common in the Non-Finnish European population (allele frequency 1.8e-06)
- Structural context available
- Literature evidence available