P65H (p.Pro65His) variant of MYL3 (Myosin light chain 3)
P65H (p.Pro65His) in MYL3 (Myosin light chain 3) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.72 / 1. The record also includes population frequency data, published literature, and structural context.
P65H (p.Pro65His) variant details
- p.Pro65His
- gnomAD 3-46860789-G-T
- Missense
- Variant Prioritization Score for Impact Estimate 0.718
- REVEL 0.67
- CADD 25.70
- PolyPhen-2 0.98
- SIFT 0.09
- Most common in the African/African-American population (allele frequency 3e-05)
- Structural context available
- Literature evidence available