V21E (p.Val21Glu) variant of MYBPC3 (Myosin-binding protein C, cardiac-type)

V21E (p.Val21Glu) in MYBPC3 (Myosin-binding protein C, cardiac-type) is a missense change. Clinical records from ClinVar, EBI, and UniProt describe it as uncertain significance in the context of Hypertrophic cardiomyopathy. The available variant effect predictions contribute to a CATVariant prioritization score of 0.85 / 1. The record also includes structural context.

V21E (p.Val21Glu) variant details