S29G (p.Ser29Gly) variant of MTHFR (P42898)
S29G (p.Ser29Gly) in MTHFR (P42898) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.33 / 1. The record also includes population frequency data and structural context.
S29G (p.Ser29Gly) variant details
- p.Ser29Gly
- TOPMed rs1235705216
- gnomAD rs1235705216
- Missense
- Variant Prioritization Score for Impact Estimate 0.328
- REVEL 0.28
- CADD 22.70
- PolyPhen-2 0.00
- SIFT 0.23
- Most common in the Latino/Admixed American population (allele frequency 6.7e-05)
- Structural context available