S108T (p.Ser108Thr) variant of MTHFR (P42898)
S108T (p.Ser108Thr) in MTHFR (P42898) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.50 / 1. The record also includes population frequency data and structural context.
S108T (p.Ser108Thr) variant details
- p.Ser108Thr
- gnomAD rs1304056030
- Missense
- Variant Prioritization Score for Impact Estimate 0.498
- REVEL 0.50
- CADD 22.10
- PolyPhen-2 0.03
- SIFT 0.56
- Most common in the Finnish in Finland (FIN) population (allele frequency 3.7e-05)
- Structural context available