M110V (p.Met110Val) variant of MTHFR (P42898)
M110V (p.Met110Val) in MTHFR (P42898) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.45 / 1. The record also includes population frequency data and structural context.
M110V (p.Met110Val) variant details
- p.Met110Val
- TOPMed rs1314255798
- Missense
- Variant Prioritization Score for Impact Estimate 0.446
- REVEL 0.46
- CADD 21.80
- PolyPhen-2 0.04
- SIFT 0.15
- Most common in the Non-Finnish European population (allele frequency 9e-07)
- Structural context available