I91T (p.Ile91Thr) variant of MTHFR (P42898)
I91T (p.Ile91Thr) in MTHFR (P42898) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.67 / 1. The record also includes population frequency data and structural context.
I91T (p.Ile91Thr) variant details
- p.Ile91Thr
- Ensembl rs1644381008
- Missense
- Variant Prioritization Score for Impact Estimate 0.667
- REVEL 0.72
- CADD 24.00
- PolyPhen-2 0.05
- SIFT 0.01
- Most common in the Non-Finnish European population (allele frequency 9e-07)
- Structural context available