V8G (p.Val8Gly) variant of MS4A1 (B-lymphocyte antigen CD20)
V8G (p.Val8Gly) in MS4A1 (B-lymphocyte antigen CD20) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.27 / 1. The record also includes population frequency data and structural context.
V8G (p.Val8Gly) variant details
- p.Val8Gly
- gnomAD rs1249627588
- Missense
- Variant Prioritization Score for Impact Estimate 0.274
- REVEL 0.06
- MetaLR 0.05
- MetaSVM -1.05
- CADD 16.50
- PolyPhen-2 0.20
- SIFT 0.06
- Most common in the 1KG:CLM population (allele frequency 0.0053)
- Structural context available