V55I (p.Val55Ile) variant of MS4A1 (B-lymphocyte antigen CD20)
V55I (p.Val55Ile) in MS4A1 (B-lymphocyte antigen CD20) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.23 / 1. The record also includes population frequency data and structural context.
V55I (p.Val55Ile) variant details
- p.Val55Ile
- Ensembl rs2135198063
- Missense
- Variant Prioritization Score for Impact Estimate 0.231
- REVEL 0.06
- MetaLR 0.01
- MetaSVM -0.99
- CADD 10.70
- PolyPhen-2 0.06
- SIFT 0.70
- Most common in the 1KG:MXL population (allele frequency 0.0081)
- Structural context available