T51S (p.Thr51Ser) variant of MS4A1 (B-lymphocyte antigen CD20)
T51S (p.Thr51Ser) in MS4A1 (B-lymphocyte antigen CD20) is a protein-truncating change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.35 / 1. The record also includes population frequency data, published literature, and structural context.
T51S (p.Thr51Ser) variant details
- p.Thr51Ser
- gnomAD 11-60462524-G-GTC
- Frameshift
- Variant Prioritization Score for Impact Estimate 0.348
- CADD 24.40
- Most common in the Middle Eastern population (allele frequency 0.0007)
- Structural context available
- Literature evidence available